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Будущее медицины: Ваше здоровье в ваших руках - Эрик Тополь

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65. G. Lyon, "Stopping 23andMe Will Only Delay the Revolution Medicine Needs," The Conversation, November 25, 2013, http://theconversation.com/stopping-23andme-will-only-delay-the-revolution-medicine-needs-20743.

66. V. Hughes, "23 a nd You," Medium, December 4, 2013, https://medium.com/matter/66e87553d22c.

67. "The FDA vs. 23andMe: A Lesson for Health Care Entrepreneurs," Knowledge at Wharton([email protected]), December 18, 2013, http://knowledge.wharton.upenn.edu/article/fda-vs-23andme-lesson-health-care-entrepreneurs/.

68. R. Bailey, "Leave 23andMe Alone," Reason.com, February 25, 2014, http://reason.com/archives/2014/02/25/leave-23andme-alone/print.

69. H. Binswanger, "FDA Says, 'No Gene Test for You: You Can't Handle the Truth,'" Forbes, November 26, 2013, http://www.forbes.com/sites/harrybinswanger/2013/11/26/fda-says-no-gene-test-for-you-you-cant-handle-the-truth/.

70. M. Allison, "Direct-to-Consumer Genomics Reinvents Itself," Nature Biotechnology 30, no. 11 (2012): 1027–1029.

71. G. J. Annas and S. Elias, "23andMe and the FDA," New England Journal of Medicine 370 (2014): 985–988.

72. M. White, "The FDA is Not Anti-Genetics," Pacific Standard, January 17, 2014: http://www.psmag.com/navigation/nature-and-technology/fda-anti-genetics-72987/.

73. C. Wood, "Does the FDA Think You're Stupid?" Casey Research, December 5, 2013, http://www.caseyresearch.com/cdd/does-the-fda-think-youre-stupid.

74. C. Farr, "23andMe Remains Optimistic Despite FDA Issues: 'We Are Not Going Anywhere' (Exclusive)," Venture Beat, December 7, 2013, http://venturebeat.com/2013/12/07/23andme-remains-defiant-despite-fda-issues-we-are-not-going-anywhere-exclusive/2/.

75. L. Downes and P. Nunes, "Regulating 23andMe to Death Won't Stop the New Age of Genetic Testing," Wired, January 1, 2014, http://www.wired.com/opinion/2014/01/the-fda-may-win-the-battle-this-holiday-season-but-23andme-will-win-the-war/.

76. N. S. Downing and J. S. Ross, "Innovation, Risk, and Patient Empowerment The FDA-Mandated Withdrawal of 23andMe's Personal Genome Service," Journal of the American Medical Association 311, no. 8 (2014): 793–794.

77. "Irresistible Force Meets Immoveable Object," Nature Biotechnology 32, no. 1 (2014): 1.

78. D. Dobbs, "The F.D.A. vs. Personal Genetic Testing," New Yorker, November 27, 2013, http://www.newyorker.com/online/blogs/elements/2013/11/the-fda-vs-personal-genetic-testing.html?printable=true&currentPage=all.

79. G. Marchant, "The FDA Could Set Personal Genetics Rights Back Decades," Slate, November 26, 2013, http://www.slate.com/articles/technology/future_tense /2013/11/_23andme_fda_letter_premarket_approval_ requirement_could_kill_at_home_genetic.html.

80. U. Francke et al., "Dealing with the Unexpected: Consumer Responses to Direct-Access BRCA Mutation Testing," PeerJ, February 12, 2013, https://peerj.com/articles/8/.

81. R. Epstein, "The FDA Strikes Again: Its Ban on Home Testing Kits Is, as Usual, Likely to Do More Harm Than Good," Point of Law, November 27, 2013: http://www.pointoflaw.com/archives/2013/11/t.php.

82. A. Wolfe, "Anne Wojcicki's Quest for Better Health Care," Wall Street Journal, June 27, 2014, http://online.wsj.com/articles/anne-wojcickis-quest-for-better-health-care-1403892088.

83. C. Bloss, N. Schork, and E. Topol, "Effect of Direct-to-Consumer Genomewide Profiling to Assess Disease Risk," New England Journal of Medicine 364, no. 6 (2011): 524–534.

84. R. C. Green and N. A. Farahany, "The FDA Is Overcautious on Consumer Genomics," Nature 505 (2014): 2.

85. R. Leuty, "23andMe's Andy Page Gets Disruptive with the Masses," San Francisco Business Times, October 22, 2013, http://www.bizjournals.com/sanfrancisco/blog/biotech/ 2013/10/23andme-andy-page-anne-wojcicki.html?page=all.

86. N. Fliesler, "Direct-to-Consumer Genetic Testing: A Case of Potential Harm," Boston Children's Hospital science and clinical innovation blog, May 5, 2014, http://vectorblog.org/2014/05/direct-to-consumer-genetic-testing-a-case-of-potential-harm/.

87. S. Pasha, "23andMe Revealed a Condition It Took My Doctors Six Years to Diagnose," Quartz, November 28, 2013, http://qz.com/151817/23andme-revealed-a-condition-it-took-my-doctors-six-years-to-diagnose/.

88. "The FDA and Thee," Wall Street Journal, November 25, 2013: http://online.wsj.com/news/articles/SB10001424052702304465604579220003539640102.

89. M. A. Hamburg, "FDA Supports Development of Innovative Genetic Tests," Wall Street Journal, December 3, 2013: http://online.wsj.com/news/articles/ SB10001424052702304011304579222111609444156.

90. F. S. Collins and M. A. Hamburg, "First FDA Authorization for Next-Generation Sequencer," New England Journal of Medicine 369 (2013): 2369–2371.

91. "Regulation of Laboratory Developed Tests (LDTs)," American Society for Clinical Pathology, 2010, http://www.ascp.org/PDF/Advocacy/Regulation-of-laboratory-developed-tests-LDTs.aspx.

92. P. Offt, Do You Believe in Magic? (New York, NY: HarperCollins, 2013).

93. A. O'Connor, "Spike in Harm to Liver Is Tied to Dietary Aids," New York Times, December 22, 2013, http://www.nytimes.com/2013/12/22/us/spike-in-harm-to-liver-is-tied-to-dietary-aids.html.

94. J. Pickrell, "Should the FDA Regulate the Interpretation of Traditional Epidemiology?" Genomes Unzipped, February 12, 2013, http://www.genomesunzipped.org/2013/12/should-the-fda-regulate-the-interpretation-of-traditional-epidemiology.php.

95. D. Dobbs, "Is the National Cancer Institute Telling Me to Remove My Breasts?" Neuron Culture, December 2, 2013, http://daviddobbs.net/smoothpebbles/is-the-national-cancer-institute-telling-me-to-remove-my-breasts/.

96. M. Eisen, "FDA vs. 23andMe: How Do We Want Genetic Testing to Be Regulated?" it is NOT junk, November 26, 2013, http://www.michaeleisen.org/blog/?p=1480.

97. "The FDA and me," Nature 504 (2013): 7–8.

98. C. Seife, "23andMe Is Terrifying, but Not for the Reasons the FDA Thinks," Scientific American, November 27, 2013, http://www.scientificamerican.com/article.cfm?id=23andme-is-terrifying-but-not-for-reasons-fda.

99. A. R. Venkitaraman, "Cancer Suppression by the Chromosome Custodians, BRCA1 and BRCA2," Science 343 (2014): 1470–1475.

100. D. B. Agus, "The Outrageous Cost of a Gene Test," New York Times, May 21, 2013, http://www.nytimes.com/2013/05/21/opinion/the-outrageous-cost-of-a-gene-test.html.

101. Supreme Court of the United States, "Association for Molecular Pathology et al. versus Myriad Genetics, Inc., et al." SCOTUS, 2013, http://www.supremecourt.gov/opinions/12pdf/12-398_1b7d.pdf.

102. M. Specter, "Can We Patent Life?" New Yorker, April 1, 2013, http://www.newyorker.com/online/blogs/elements/2013/04/myriad-genetics-patent-genes.html.

103. E. Marshall, "Supreme Court Rules Out Patents on 'Natural' Genes," Science 340 (2013): 1387–1388.

104. N. Feldman, "The Supreme Court's Bad Science on Gene Patents," Bloomberg View, June 13, 2013, http://www.bloombergview.com/articles/2013-06-13/the-supreme-court-s-bad-science-on-gene-patents.

105. R. Cook-Deegan, "Are Human Genes Patentable?" Annals of Internal Medicine 159, no. 4 (2013): 298–299.

106. N. Totenberg, "Supreme Court Asks: Can Human Genes Be Patented?" NPR Shots, April 15, 2013, http://www.npr.org/blogs/health/2013/04/15/177035299/supreme-court-asks-can-human-genes-be-patented.

107. E. J. Topol, "DNA & Supreme Court: Nature Cannot Be Patented," Union-Tribune San Diego, April 27, 2013, http://www.utsandiego.com/news/2013/apr/27/dna-supreme-court-nature-cannot-be-patented/.

108. J. Guo, "The Supreme Court Reveals Its Ignorance of Genetics," New Republic, June 13, 2013, http://www.newrepublic.com//article/113476/supreme-court-genetics-ruling-reveals-judges-ignorance.

109. D. J. Kevles, "Can They Patent Your Genes?" New York Review of Books, March 7, 2013, http://www.nybooks.com/articles/archives/2013/mar/07/can-they-patent-your-genes/.

110. C. Y. Johnson, "Eric Lander Weighs In on Gene Patenting Case," Boston Globe, February 26, 2013, http://www.bostonglobe.com/lifestyle/health-wellness/2013/02/26/eric-lander-human-genome-project-leader-weighs-supreme-court-gene-patenting-case/EjRae5IRYwUYRVLg6NXTZL/story.html.

111. L. O. Gostin, "Who Owns Human Genes? Is DNA Patentable?" Journal of the American Medical Association 310, no. 8 (2013): 791–792.

112. G. Mohan, "Researchers Hail Supreme Court Decision on Gene Patent," Los Angeles Times, June 13, 2013, http://www.latimes.com/news/science/sciencenow/la-sci-sn-gene-patent-reaction-20130613,0,6362625,print.story.

113. H. Ledford, "Myriad Ruling Causes Confusion," Nature 498 (2013): 281–282.

114. S. Reardon, "I Discovered the BRCA Genes," Slate, June 15, 2013, http://www.slate.com/articles/health_and_science/ new_scientist/2013/06/brca_gene_discovery_mary_ claire_king_says_the_supreme_court_is_right_not.html.

115. J. Carlson, "Myriad Stock Falls as Competitors Offer Lower Prices for Gene Testing," Modern Healthcare, June 13, 2013, http://www.modernhealthcare.com/article/20130613/NEWS/306139947/.

116. J. Walker, "Reimbursement for Breast-Cancer Risk Test to Be Cut," Wall Street Journal, December 29, 2013, http://online.wsj.com/news/article_email/ SB10001424052702304361604579288591617575358 -lMyQjAxMTA0MDIwOTEyNDkyWj.

117. C. Gunter, "SCOTUS Ruling Means Cheaper Genetic Testing," Double X Science, June 14, 2013, http://www.doublexscience.org/myriad-genetics-ruling/.

118. J. Carlson, "'The Cost Will Drop,'" Modern Healthcare, June 15, 2013, http://www.modernhealthcare.com/article/ 20130615/MAGAZINE/306159974/.

119. M. Scudellari, "Myriad Sues Developers of Competing Breast Cancer Tests," Nature Medicine 19, no. 8 (2013): 948.

120. R. Nussbaum, "Free Our Genetic Data," MIT Technology Review, July 25, 2013, http://www.technologyreview.com/view/517526/free-our-genetic-data/.

121. "Life on Mars? Discover Magazine Announces the Top 100 Stories of 2013," Discover, Jan – Feb 2014, http://discovermagazine.com/2014/jan-feb.

Глава 5

1. A. Pentland, «How Big Data Can Transform Society for the Better,» Scientific American, October 1, 2014, http://www.scientificamerican.com/article/how-big-data-can-transform-society-for-the-better/.

2. S. Lohr, "Sizing Up Big Data, Broadening Beyond the Internet," New York Times, June 19, 2013, http://bits.blogs.nytimes.com/2013/06/19/sizing-up-big-data-broadening-beyond-the-internet/.

3. "Epidemiolog y," Wikipedia, accessed August 13, 2014, 2014, http://en.wikipedia.org/wiki/Epidemiology.

4. J. L. Gardy et al., "Whole-Genome Sequencing and Social-Network Analysis of a Tuberculosis Outbreak," The New England Journal of Medicine 364 (2011): 730–739.

5. E. Topol, "Individualized Medicine from Prewomb to Tomb," Cell 157 (2014): 241–253.

6. T. Simonite, "Life's Trajectory Seen Through Facebook Data," MIT Technology Review, April 24, 2013, http://www.technologyreview.com/view/514186/lifes-trajectory-seen-through-facebook-data/.

7. A. Regalado, "Stephen Wolfram on Personal Analytics," MIT Technology Review, May 8, 2013, http://www.technologyreview.com/news/514356/stephen-wolfram-on-personal-analytics/.

8. N. A. Christakis and J. H. Fowler, Connected (New York, NY: Little, Brown and Co., 2009).

9. "Phenotype," Wikipedia, accessed August 13, 2014, http://en.wikipedia.org/wiki/Phenotype.

10. "Microphones as Sensors: Teaching Old Microphones New Tricks," The Economist, June 1, 2013, http://www.economist.com/news/technology-quarterly/21578518-sensor-technology-microphones-are-designed-capture-sound-they-turn-out.

11. G. Slabodkin, "Study: iPhone App for Speech Laterality Just as Reliable as Lab Brain Tests,"FierceMobileHealthcare, February 12, 2013, http://www.fiercemobilehealthcare.com/story/study-iphone-app-speech-laterality-just-reliable-lab-brain-tests/2013-02-12.

12. I. Ezkurdia et al., "Multiple Evidence Strands Suggest That There May Be as Few as 19,000 Human Protein-Coding Genes," Human Molecular Genetics, June 16, 2014, http://www.ncbi.nlm.nih.gov/pubmed/24939910.

13. A. Butte, "Should Healthy People Have Their Genomes Sequenced at This Time?" Wall Street Journal, February 15, 2013, http://online.wsj.com/news/articles/SB1000087 2396390443884104577645783975993656.

14. E. C. Hayden, "Non-Invasive Method Devised to Sequence DNA of Human Eggs," Nature News & Comment, December 19, 2013, http://www.nature.com/news/non-invasive-method-devised-to-sequence-dna-of-human-eggs-1.14412.

15. R. W. Taylor et al., "Use of Whole-Exome Sequencing to Determine the Genetic Basis of Multiple Mitochondrial Respiratory Chain Complex Deficiencies," Journal of the American Medical Association 312, no. 1 (2014): 68–77.

16. J. Lupski, "Genetics. Genome Mosaicism– One Human, Multiple Genomes," Science 341 (2013): 358–359.

17. M. J. McConnell et al., "Mosaic Copy Number Variation in Human Neurons," Science 342 (2013): 632.

18. I. Cho and M. Blaser, "The Human Microbiome: At the Interface of Health and Disease," Nature Reviews Genetics 13 (2012): 260–270.

19. R. Chen et al., "Personal Omics Profiling Reveals Dynamic Molecular and Medical Phenotypes," Cell 148 (2012): 1293–1307.

20. E. Aiden and J.-B. Michel, "The Predictive Power of Big Data," Newsweek, December 25, 2013, http://www.newsweek.com/predictive-power-big-data-225125.

21. R. Almeling, "The Unregulated Sperm Industry," New York Times, December 1, 2013, http://www.nytimes.com/2013/12/01/opinion/sunday/the-unregulated-sperm-industry.html.

22. M. Allyse and M. Michie, "You Can't Predict Destiny by Designing Your Baby's Genome," Wall Street Journal, November 8, 2013, http://online.wsj.com/news/articles/SB10001424 052702304448204579182353852538422.

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Сергей
Сергей 24.01.2024 - 17:40
Интересно было, если вчитаться