Мусорная ДНК. Путешествие в темную материю генома - Несса Кэри
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Глава 181. Ameres SL, Zamore PD. Diversifying microRNA sequence and function. Nat Rev Mot Celt Biol. 2013 Aug; 14(8):475-88.
2. Более подробное описание классов малых РНК см. в: Castel SE, Martienssen RA. RNA interference in the nucleus: roles for small RNAs in transcription, epigenetics and beyond. Nat Rev Genet. 2013 Feb; 14(2): 100—12.
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24. Вот один из обзоров, посвященных данной теме: Suzuki Н, Maruyama R, Yamamoto Е, Kai М. Epigenetic alteration and microRNA dysregulation in cancer. Front Genet. 2013 Dec 3;4:258. eCollection 2013.
25. Kleinman CL, Gerges N, Papillon-Cavanagh S, Sin-Chan P, Pramatarova A, Quang DA, Adoue V, Busche S, Caron M, Djainbazian H, Bemmo A, Fontebasso AM, Spence T, Schwartzentruber J, Albrecht S, Hauser P, Garami M, Klekner A, Bognar L, Montes L, Staffa A, Montpetit A, Berube P, Zakrzewska M, Zakrzewski K, Liberski PP, Dong Z, Siegel PM, Duchaine T, Perotti C, Fleming A, Faury D, Remke M, Gallo M, Dirks P, Taylor MD, Sladek R, Pastinen T, Chan JA, Huang A, Majewski J, JabadoN. Fusion ofTTYHl with theC19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor ETMR. Nat Genet. 2014 Jan; 46 (1):39-44.
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Глава 191. Краткий перечень лекарств, активнее всего продававшихся за последние годы, см. в: http://www.fiercepharma.com/special-reports/ 15-best-selling-drugs-2012.
2. Этой сфере посвящено множество блогов. Напр.: http://biop-harmconsortium.com/rnai-therapeutics-stage-a-comeback.
3. Подробнее см. в: http://ghr.nlm.nih.gov/condition/transthyre-tin-amyloidosis.
4. http://investors.alnylam.com/releasedetail.cfm?ReleaseID-805999.
5. Все новости о данной программе можно найти здесь: http://mir-narx.com/pipeline/mirna-MRX34.html.
6. Koval ED, Shaner C, Zhang P, du Maine X, Fischer K, Tay J, Chau BN, Wu GF, Miller TM. Method for widespread microRNA-155 inhibition prolongs survival in ALS-model mice. Hum Mol Genet. 2013 Oct 15; 22(20):4127-35.
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8. Очень хороший обзор, посвященный тому, как антисмысловая экспрессия может регулировать гены: Pelechano V, Stein me tz LM. Gene regulation by antisense transcription. Nat Rev Genet. 2013 Dec; 14(12):880-93.
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10. https://www.bhf.org.uk/heart-matters-online/august-septem-ber-2012/medical/familial-hypercholesterolaemia.aspx.
11. http://www.medscape.com/viewarticle/804574_5.